Osteoclasts

Osteoclasts

Sale price  £149.99 Regular price  £199.99
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Osteoclasts

Osteoclasts

Morphology, Functions & Clinical Implications

Written by Alexander J Brown

Sale price  £149.99 Regular price  £199.99
Out of stock
Osteoclasts are highly specialised cells, derived from the hematopoietic lineage, that resorb mineralised bone matrix. Osteoclast precursors can be recruited to the bone remodelling sites by specific cytokines in the microcellular environment, including some secreted by osteoblasts, fibroblasts, and osteocytes. In this book, the authors present current research in the study of the morphology, functions and clinical implications of osteoclasts. Topics include osteoclast formation and function and its risk in skeletal bone disease; the high osteoclastogenic potential of human osteosarcoma cells; osteoclast biology regarding Paget's disease and p62 mutations; the role of immuno-skeletal interface in the regulation of osteoclast formation; and osteoclasts in patients with neurofibromatosis 1.
ISBN-13
9781620813065
Publication date
19 October 2012
Format
Hardback
Pages
169
Dimensions
180 x 260 mm
Language
English

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