Overview of Genetic Factors & Environmental Triggers in the Pathogenesis of Tourette's Syndrome

£46.49 £61.99

Overview of Genetic Factors & Environmental Triggers in the Pathogenesis of Tourette's Syndrome

Name: Overview of Genetic Factors & Environmental Triggers in the Pathogenesis of Tourette's Syndrome
Brand: Nova Science Publishers, Inc (US)
Price: 46.49 GBP
Availability: InStock

Written by Cong-Yi Wang, Shi-Guo Liu, Ping Yang, Zhimin Miao, Qian Dong, Changgui Li and Wei Wang

£46.49 £61.99

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Tourette's syndrome (TS) is an inheritable, childhood-onset neuropsychiatric disorder characterised by the presence of motor and phonic tics. Despite decades of extensive studies, the exact disease aetiology remains poorly understood. It is believed that susceptibility to TS is determined by the interactions of multiple genetic loci with unknown environmental factors. As a result, a great deal of research has been focused on identifying TS susceptibility genes. Thus far, at least 12 susceptibility loci have been suggested by genome-wide screenings, but none of them has been replicated probably due to genetic heterogeneity. Candidate gene approach has also suggested evidence for several genes relevant to neuronal signalling such as dopamine receptor and serotonin receptor. This book discusses the current state of genetic studies in TS susceptibility.

ISBN-13: 9781616687489
Publisher: Nova Science Publishers Inc
Imprint: Nova Science Publishers, Inc (US)
Publication date: 22 September 2010
Format: Paperback
Pages: 59
Dimensions: 140 x 215 mm
Language: English