Protein Misfolding

Protein Misfolding

Sale price  £149.99 Regular price  £199.99
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Protein Misfolding

Protein Misfolding

Sale price  £149.99 Regular price  £199.99
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Proteins occasionally exhibit the potential to adopt alternate folds under natural or artificial conditions. These conformational changes can lead to the creation of disease-forming amyloid plaques or accumulation of insoluble aggregates in over-expressed recombinant proteins. Because alternate folds challenge the traditional notion of structurally defined proteins and frequently lead to problems in natural and laboratory settings, it is tempting to characterise structurally ambiguous proteins as ill-behaved. Unfortunately, this perspective masks the positive role structural ambiguity can play in protein function and evolution. This book provides leading-edge research on the study of protein misfolding from researchers all over the globe.
ISBN-13
9781604568813
Publication date
1 October 2008
Format
Hardback
Pages
234
Dimensions
185 x 260 mm
Illustrations
tables & charts
Language
English

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