Hepatic Steatosis

Hepatic Steatosis

Sale price  £166.49 Regular price  £221.99
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Hepatic Steatosis

Hepatic Steatosis

Clinical Risk Factors, Molecular Mechanisms and Treatment Outcomes

Written by Sergio Santos

Sale price  £166.49 Regular price  £221.99
Out of stock
In the last few years, human metabolic disorders have become some of the most prevalent and prejudicial diseases worldwide. Hepatic steatosis, among many health problems, has several risk factors related to the disease prognosis such as obesity, nutritional problems, diabetes, hypertension, hyperuricemia, and even sleep apnea. Alcohol abuse also can lead to a severe liver-steatosis state. The progression of hepatic steatosis can lead to complications such as cryptogenic cirrhosis and hepatocellular carcinoma. Drug therapy has instead been focused on the mitigation of risk factors, however new potential therapeutic perspectives are being discussed. This book presents the origins, diagnosis and epidemiology of hepatic steatosis with new perceptions. The authors also aimed to show the molecular basis and signaling involved in liver disorders, discussing the inflammatory process, lipid metabolism and angiogenesis mechanisms. The role of nutrition in the treatment and development of steatosis was also presented and new advances were highlighted. Recent studies revealed the need for the use of bariatric surgery, functional foods and the modulation of endogenous systems, such as the sirtuins and renin-angiotensin systems, to treat liver disease. In this context, we aimed to introduce, review and discusses one of the most widespread metabolic disorders in the world: hepatic steatosis and its repercussions.
ISBN-13
9781633214033
Publication date
1 September 2014
Format
Hardback
Pages
306
Dimensions
254 x 178 mm
Language
English

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