New Developments on Signal Transduction Research

£159.74 £212.99

New Developments on Signal Transduction Research

Name: New Developments on Signal Transduction Research
Brand: Nova Science Publishers, Inc (US)
Price: 159.74 GBP
Availability: OutOfStock

Written by Masayoshi Yamaguchi

£159.74 £212.99

Out of stock

Signal transduction plays a pivotal role in cell regulation. Hormones, cytokines and neurotransmitters bind to their specific receptors in the plasma membranes of cells. The receptors of many hormones are coupled to G-protein coupled signalling pathways. Insulin and growth factors are coupled to receptor-linked kinase. The second messenger is generated in cells once the first messenger binds to the receptors of plasma membranes. Cyclic adenosine monophosphate (cyclic AMP), inositol 1,3,5-triphosphate (IP3) and calcium ion (Ca2+) have been demonstrated to play a role as a second messenger in cells. The pivotal role of Ca2+ in cellular regulation was established with the finding of calmodulin and protein kinase C that modulates the effect of Ca2+ in the regulation of cellular functions. Many receptor classes and their downstream kinases activate Erk, Akt, Stat, Smad, NF-κB and other cascades to regulate gene expression and cellular function. This book provides recent research in the study of the new developments in signalling transduction in cells.

ISBN-13: 9781626182301
Publisher: Nova Science Publishers Inc
Imprint: Nova Science Publishers, Inc (US)
Publication date: 17 May 2013
Format: Hardback
Pages: 250
Dimensions: 260 x 180 mm
Language: English