Molecular Aspects of G Protein-Coupled Receptors

Molecular Aspects of G Protein-Coupled Receptors

Sale price  £99.74 Regular price  £132.99
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Molecular Aspects of G Protein-Coupled Receptors

Molecular Aspects of G Protein-Coupled Receptors

Interacting Proteins & Function

Sale price  £99.74 Regular price  £132.99
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In the recent years studies based on two-hybrid screens, proteomic, biochemical and cell biology approaches, have shown that intracellular domains of G protein-coupled receptors (GPCR) or heptaspanning membrane receptors (HSMRs) interact with intracellular proteins. These interactions are the basis of a protein network associated to these receptors which includes scaffolding proteins containing one or several PDZ (post-synaptic density-95, discs large, zona occludens-1) domains, signalling proteins and proteins of the cytoskeleton. The present book is focused on the emerging evidence for interactions of G protein-coupled receptors with scaffolding, cytoskeletal and signalling proteins that will play a role in the targeting, anchoring and functioning of these receptors in the plasma membrane, thus contributing to cell development and plasticity.
ISBN-13
9781600219153
Publication date
1 November 2007
Format
Hardback
Pages
309
Dimensions
180 x 260 mm
Illustrations
tables & charts
Language
English

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