Gene Expression: Developmental Processes, Disease Mechanisms, and Targeted Therapies

This volume includes four Chapters that detail the developmental processes, disease mechanisms, and targeted therapies surrounding gene expression. Chapter 1 aims to pave the way for innovative therapeutic interventions and ultimately improve the quality of life for women affected by ovarian disorders. Chapter 2 provides an in-depth understanding of the efficacy of current treatments, combination strategies, and new emerging therapies, highlighting the importance of an individualized approach to the treatment of PD. Chapter 3 investigates the expression profile and molecular pathways underlying Interferon-stimulated gene 15 (ISG15) gene regulation, its functional implications, and its relevance to the detection and control of glioblastoma and medulloblastoma. Finally, Chapter 4 examines the mRNA patterns of dopamine D2 and D5 receptors in the thalamus and associated with persistent inflammatory pain in a rat model of 6-hydroxydopamine (6-OHDA) Parkinson's disease.