{"product_id":"9781600218200","title":"Dopamine Research Advances","description":"Dopamine is a phenethylamine naturally produced by the human body. In the brain, dopamine functions as a neurotransmitter, activating the five types of dopamine receptor -- D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine can be supplied as a medication that acts on the sympathetic nervous system, producing effects such as increased heart rate and blood pressure. However, since dopamine cannot cross the blood-brain barrier, dopamine given as a drug does not directly affect the central nervous system. To increase the amount of dopamine in the brains of patients with diseases such as Parkinson's disease and Dopa-Responsive Dystonia, L-DOPA (levodopa), which is the precursor of dopamine, can be given because it can cross the blood-brain barrier. This book presents new research in the field.","brand":"Nova Science Publishers, Inc (US)","offers":[{"title":"Default Title","offer_id":65426682773853,"sku":null,"price":149.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1041\/3893\/2573\/files\/9781600218200.jpg?v=1789372083","url":"https:\/\/shop.gazellebookservices.co.uk\/products\/9781600218200","provider":"Gazelle Book Services","version":"1.0","type":"link"}